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Neurodegenerative diseases represent some of the most significant public health challenges of the 21st century: they are chronic, common and untreatable. 

Today, one-third of adults over 85 years of age have some form of dementia. As our population ages over the next 25 years, the prevalence of these diseases is expected to double.

The science of these diseases is complex – the easy answers have been ruled out. 

At the Tanz Centre, we are prepared to meet this challenge. Our researchers have made many of the most important discoveries of the past two decades concerning the genetics of Alzheimer’s and other diseases. We are determined to discover and invent effective diagnostics and therapies that will stop these devastating diseases.

To learn more about our research areas and the science behind the neurodegenerative diseases studied at the Tanz Centre, please explore the links below:

ALS

Alzheimer’s Disease

Frontotemporal Dementia

Parkinson's

Prion Diseases

See All News
Aug 23, 2023

Tanz Centre Research Challenges Long-Held View of Early-Stage Alzheimer's Disease

Researchers at the Tanz Centre have used novel techniques to uncover which subtypes of brain cells express genetic material that produces tau, a key protein involved in the development of the neurodegenerative disease progressive supranuclear palsy (PSP).
Jun 21, 2023

Tanz Centre Research Challenges Long-Held View of Early-Stage Alzheimer's Disease

Recent research from the Tanz Centre for Research in Neurodegenerative Diseases, published in Scientific Reports, is challenging long-held views of how a hormone called somatostatin influences the earliest stages of Alzheimer’s disease.
May 30, 2023

Small Rodent’s Unique Properties Key to Studying Prion Disease

A small rodent called the bank vole may hold the key to a better understanding of rare neurodegenerative prion diseases, according to new research from the University of Toronto.
Apr 19, 2023

Researchers Identify a Potential New Therapeutic Target in Parkinson’s Disease

In a study published in Nature Communications, a team led by Krembil Brain Institute scientists Lorraine Kalia and Suneil Kalia, and University of Toronto researcher Philip M. Kim, identified a protein-protein interaction that contributes to Parkinson’s disease.
Apr 5, 2023

Race with Steph: Ten Triathlons in Ten Provinces to End Alzheimer’s

Stephanie Fauquier is racing across the country to build a national movement to raise awareness and funds for Alzheimer's research at U of T in honour of her mother, Dr. Robin McLeod.
Mar 30, 2023

Tanz Centre Team Finds Crucial Link in Understanding ALS

Researchers at the University of Toronto have shown that loss of a key protein in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) may contribute to the underlying cause of both diseases.

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Microscope analysing slide